Over the last 15 years, high-performance liquid chromatogra phy (LC) has made the transition from an instrument used only by experts in research labs to a tool used for routine applications by relatively unskilled workers. With this transition have come in instrumentation and column technology. In major advances the past, the operator had to be a jack-of-all-trades, with a screw driver, soldering iron, and various wrenches as constant compan ions in the LC lab. Today, many instruments contain micropro cessors as powerful as those of mainframe computers of earlier days. With this technology has come a variety of self-diagnostic tools that allow the LC system to locate many of its own prob lems. Traditionally, well-honed LC troubleshooting skills have been a result of years of work at the bench. Today the LC system itself often can do a better job of troubleshooting than the operator can. Yet many of the problems of the past are still the major problems of today: air bubbles, check valves, detector lamps, and, of course, problems with the separation. An added pressure on the operator of today's LC system is that of productivity-the lab often cannot afford unnecessary downtime. This means that the operator has to be a troubleshooting expert, or has to have that expertise at his or her fingertips. The present book was written to provide this expertise in an easy-to-use format for users at all levels of experience.A Comprehensive Approach to Troubleshooting LC Equipment and Separations John W. Dolan, Lloyd R. Snyder ... 2000 2010 2020 2040 2050 2060 2070 2080 2120 2130 aPressure is high aPressure normal, low, or erratic Go to Pressure ( 1020A) Where is the leak? ... check valve (do not overtighten) Tighten or replace fitting a- OK aS. GET HELP (check service manual) 2220 2230 2240 2250 2290 anbsp;...
|Title||:||Troubleshooting LC Systems|
|Author||:||John W. Dolan, Lloyd R. Snyder|
|Publisher||:||Springer Science & Business Media - 1989-03-01|