Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimeras disease, epilepsy, alcoholism, substance abuse and others are some of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: aNeuropsychological Endophenotypes and Biomarkersa (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), aNeuroanatomical and Neuroimaging Endophenotypes and Biomarkersa, aMetabolic and Peripheral Biomarkersa and aMolecular Genetic and Genomic Markersa. The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.Schizophr Bull 2008;34(4):774a790 41. Chan RC, Gottesman II. Neurological soft signs as candidate endophenotypes for schizophrenia: a shooting star or a Northern star? Neurosci Biobehav Rev 2008;32:957a971 42. Egan MF, Goldberg TEanbsp;...
|Title||:||The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes|
|Author||:||Michael S. Ritsner|
|Publisher||:||Springer Science & Business Media - 2009-04-21|