The collection of systems represented in this volume is a unique effort to reflect the diversity and utility of models used in biomedicine. That utility is based on the consideration that observations made in particular organisms will provide insight into the workings of other, more complex systems. This volume is therefore a comprehensive and extensive collection of these important medical parallels.The CEL I method does miss some mutations and produces a considerable amount of false-positive dots that have to be followed up by an ... awards a score to putative heterozygous positions, for which the original sequence trace was individually scanned by the eye. All potential mutations that pass this manual selection are repeated by an independent PCR and sequencing reaction for verification.
|Title||:||Sourcebook of Models for Biomedical Research|
|Publisher||:||Springer Science & Business Media - 2008-03-07|