Neural crest is a vertebrate-specific population of embryonic precursor cells thought to have been essential in vertebrate evolution. During development, a group of naive ectoderm cells are induced to become neural crest and then undergo series of developmental events to give rise to diverse derivatives. Failure of these events often leads to malfunction of neural crest derived tissues and organs. This thesis focuses on the genetic regulation of two events during neural crest development, induction and differentiation.At sphere stage (4 hpf), about 100 cells were withdrawn from each donor embryo with a manual-drive syringe fitted with ... in situ hybridization and to reveal biotin with an ABC kit (Vector Labs, Burlingame, CA) and DAB as previously described anbsp;...
|Title||:||Roles for Activator Protein 2 (AP-2) Transcription Factors in Zebrafish Neural Crest Development|
|Publisher||:||ProQuest - 2008|