Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory or population studies into clinical application to reduce incidence of cancer , morbidity and mortality. It is becoming increasingly evident that cancer is a preventable disease. The IVth International Symposium on Translational Cancer Research held in Udaipur, India in December 2011, discussed various aspects of the biological processes in cancer cells and approaches to cancer prevention. A few contributions from this meeting are presented in this book, providing an in depth analysis of data on cancer prevention and therapeutics. These contributions are either critical reviews or research reports. The topics discussed include evidence-based nutritional recommendations for cancer patients and survivors, risk factors such as stress, enrichment of tumour stem cells by anticancer drug treatment contributing to tumour recurrence and the mechanism of anticancer effects of various natural products. Chemosensitizing effect of curcumin, anti-cancer effect of products from neem, action of sulforaphane and cytotoxic effect of a number of novel synthetic coordination complexes of trace metals have been discussed. Novel molecular targets of angiogenesis and molecular basis of the gender bias to thyroid cancer have also been discussed . This book provides useful information on translational cancer research to clinicians and biomedical scientists.... (Pongo pygmaeus), macaque (Macaca mulatta), horse (Equus caballus), cow ( Bos taurus), dog (Canis familiaris), mouse (Mus musculus), and ... and UniProtKB /Swiss-Prot (http://www.uniprot. org/uniprot/) into four groups: (1) replication, repair, and recombination (RRR); ... Heat map was generated to represent repeat motif frequencies by using web interface of aMatrix2pnga (Pavlidis and Noble 2003).
|Title||:||Perspectives in Cancer Prevention-Translational Cancer Research|
|Author||:||Sudhakaran Perumana, V. Oommen, M. Radhakrishna Pillai|
|Publisher||:||Springer Science & Business Media - 2013-10-25|