On-Line Hemodiafiltration: The Journey and the Vision

On-Line Hemodiafiltration: The Journey and the Vision

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On-line HDF represents a major technical development in the delivery of hemodialysis therapy: It combines the properties of increased diffusion available in current high-flux membranes with convective removal of between 6 and 30 liters per treatment and requires the use of ultrapure water and online filtration of replacement fluid. On-line HDF has been successfully introduced in Europe and Asia and is routinely prescribed for dialysis patients in these regions.The book at hand summarizes the history and achievements of on-line HDF in four parts: A report of the technological development in both machine and fiber/dialyzer is followed by a description of the challenges encountered in the evolution of on-line HDF, collecting the accounts of clinical key opinion leaders who had been involved in its early application. The third part presents a comprehensive review of the clinical results achieved with on-line HDF from its inception to the present times, in which it represents the clinical golden standard. The fourth and final part is dedicated to on-line HDF as a a€˜visiona€™ for the future.In such a case, one can use a#39;automated manuala#39; or a#39;alarm-freea#39; treatment. Here we prescribe a Qi value automatically by adjusting hematocrit and total protein values to obtain a Qi value for manual prescription at the beginning of the session.

Title:On-Line Hemodiafiltration: The Journey and the Vision
Author:G. Krick, C. Ronco
Publisher:Karger Medical and Scientific Publishers - 2011-12-20


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