The diagnosis of myelodysplastic syndromes (MDS), a heterogeneous group of clonal hematopoietic disorders, is being made with increasing frequency over the past decade owing to increased recognition, improved understanding, and an aging population. This book, completely updated since the first edition, summarizes in a concise and focused way the current knowledge of all aspects of MDS. Clinical presentation, etiology, epidemiology, molecular biology, classification, and staging are all discussed. Clear guidance is provided on diagnosis and differential diagnosis, and treatment strategies are explained in detail, including administration of hematopoietic growth factors, biologically based treatment, hematopoietic stem cell transplantation, and supportive care. Additional chapter is devoted to MDS in children. This practically oriented book will be of value to a broad spectrum of students and practitioners in the field.... data from human studies and clear evidence of the bone marrow as a site of benzene toxicity (Golding and Watson 1999). ... 2010). Few of these cohort studies included MDS or reported on it separately, but a couple noted significantly higher numbers of MDS ... 1991; Honda et al. ... These studies are subject to the same limitations as the studies on pesticides, in terms of the possibility of recall bias andanbsp;...
|Author||:||H. Joachim Deeg, David T. Bowen, Steven D. Gore, Torsten Haferlach, Michelle M. Le Beau, Charlotte Niemeyer|
|Publisher||:||Springer Science & Business Media - 2013-07-08|