Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.Studies of immunoglobulin (Ig) genes have been one of the major focal points in modern biology. ... much to our understanding of fundamental genetic and cellular processes, ranging from transcription, differential RNA processing, site- and region-specific ... Gene targeted mutational studies had also begun to be employed to test the function of Ig genes and some of their regulatory sequences as well asanbsp;...
|Title||:||Molecular Biology of B Cells|
|Author||:||Michael Reth, Andreas Radbruch, Frederick Alt, Tasuku Honjo, Michael Neuberger|
|Publisher||:||Academic Press - 2004-02-19|