Lysosomes are membrane-surrounded organelles which are present in all animal cells. This book summarizes the knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, and more.... ago, the first molecular mechanisms have only been recently revealed due to the discovery of autophagy-defective yeast mutants. ... 1), and 3) chaperone- mediated autophagy. ... In crinophagy, secretory vesicles directly fuse with lysosomes, which leads to degradation of the granule contents. ... By definition, autophagosomes, also called initial autophagic vacuoles *Eeva-Liisa Eskelinen aInstitute ofanbsp;...
|Publisher||:||Springer Science & Business Media - 2005-08-03|