With increasing emphasis being placed on screening and early prevention in cancer, this textbook examines the various methods and interventions used in screening in lung cancer, and presents a detailed review of the approaches to prevention and treatment of early disease. It will be of particular interest to lung cancer and respiratory medicine specialists.... a fully invasive lung cancer.23 The original description of a#39;field cancerizationa#39; by Slaughter and co-workers suggested that ... 3 and 9 losses have been associated with smoking and they remain detectable many years after smoking cessation.31, 33 ... Phosphorylation of the retinoblastoma (RB) gene is reduced by p53, thereby halting the cell cycle at check-point G1/S enabling DNA repair or apoptosis.
|Title||:||IASLC Textbook of Prevention and Early Detection of Lung Cancer|
|Author||:||Fred R. Hirsch, Paul A. Bunn, James L. Mulshine, Harubumi Kato|
|Publisher||:||CRC Press - 2005-11-12|