?????????????While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin. ?Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication. The audience for this book is mainly newly established scientists ?and graduate students. Rather than going into the more specific areas of recent research on chromatin the chapters in this book give a strong, updated groundwork about the topic. Some the fundamentals that this book will cover include the structure of chromatin and biochemistry and the enzyme complexes that manage it.... DH (2003) Knockout targeting of the Drosophila nap1 gene and examination of DNA repair tracts in the recombination products. ... Nature 286(5775):763a767 Laskey RA, Honda BM, Mills AD, Finch JT (1978) Nucleosomes are assembled by an ... Genetics 171(4):1513a1522 Liu WH, Roemer SC, Port AM, Churchill ME (2012) CAF-1-induced oligomerization of histones ... Wu WH, Ranjan A, Backus J , Sen S, Lewis M, Bai Y, Wu C (2007) Chz1, a nuclear chaperone for histone H2AZ.
|Title||:||Fundamentals of Chromatin|
|Author||:||Jerry L. Workman, Susan M. Abmayr|
|Publisher||:||Springer Science & Business Media - 2013-12-04|