This text traces developments in rational drug discovery and combinatorial library design with contributions from 50 leading scientists in academia and industry who offer coverage of basic principles, design strategies, methodologies, software tools and algorithms, and applications. It outlines the fundamentals of pharmacophore modelling and 3D Quantitative Structure-Activity Relationships (QSAR), classical QSAR, and target protein structure-based design methods.Sci., 1996, 36: 572-584. Cerius2 v4.0. Molecular Simulations Inc., San Diego, CA. Catalyst v3.5. Molecular Simulations Inc., San Diego, CA. The Daylight Theory Manual. http://www.daylight.com. ISIS/Base, MDL Information Systems, Sananbsp;...
|Title||:||Combinatorial Library Design and Evaluation|
|Author||:||Arup Ghose, Vellerkad Viswanadhan|
|Publisher||:||CRC Press - 2001-06-26|