The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60, 000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possibleLi Y, Huang J, Zhao YL, He J, Wang W, Davies KE, et al. ... Miele ME, Robertson G, Lee JH, Coleman A, McGary CT, Fisher PB, et al. ... detected by metaphase comparative genomic hybridization with laser capture or manual microdissection: 6p gains may predict poor outcome. ... Genes Chromosomes Cancer 46:155a162 .
|Author||:||Sverre Heim, Felix Mitelman|
|Publisher||:||John Wiley & Sons - 2015-06-29|