Reviews the latest research in the field for researchers and clinicians. After a general introduction to DNA base excision repair, chapters cover uracil DNA glycosylases, repair of oxidized purines in DNA, mammalian mismatch-specific DNA glycosylases, repair of apurinic/apyrimidic sites in DNA by AP endonucleases, mutagenesis of abasic sites, a proCalf 5a#39; to 3a#39; exo/endonuclease must slide from a 5a#39; end of the substrate to perform structure-specific cleavage. ... deletion of the RAD27 gene, a structural homolog of the RAD2 nucleotide excision repair gene. l Bacteriol 1995; 177(2):364-371.
|Title||:||Base Excision Repair of DNA Damage|
|Author||:||Ian D. Hickson|
|Publisher||:||Springer Science & Business Media - 1997-01-01|