Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. qAntibody Engineeringq provides a comprehensive toolbox covering the well-established basics but also many exciting new techniques. The protocols reflect the latest qhands onq knowledge of key laboratories in this still fast-moving field. Newcomers will benefit from the proven step-by-step protocols, which include helpful practical advice; experienced antibody engineers will appreciate the new ideas and approaches. The book is an invaluable resource for all those engaged in antibody research and development.Mol Immunol 34:237a253 Barbas CF (2001) Phage display: a laboratory manual, protocol 10.5. ... Hanna N, Raab RW (1992) European patent 1, 266, 965 B1, 24 Jun 1992 Pelat T, Hust M, Laffly E, Condemine F, Bottex C, Vidal D, ... Antimicrob Agents Chemother 51:2758a2764 Rondot S, Koch J, Breitling F, Du Ibel S (2001 ) A helper phage to improve single-chain antibody presentation in phage display.
|Author||:||Roland E. Kontermann, Stefan Dübel|
|Publisher||:||Springer Science & Business Media - 2010-03-10|