Chronic Obstructive Pulmonary Disease (COPD) is a progressive, largely irreversible lung condition characterised by airflow obstruction. Although cigarette smoking is the single most important risk factor in its development, other associations and risk factors are thought to have increasing relevance throughout the world. COPD is usually managed in primary care, although it is commonly under-diagnosed, and is one of the most common medical conditions necessitating admission to hospital. The second edition of the ABC of COPD provides the entire multidisciplinary team with a reliable, up-to-date and accessible account of COPD. Extensively updated by experienced clinicians - including new chapters on spirometry, inhalers, oxygen, death, dying and end of life issues - this ABC is an authoritative and practical guide for general practitioners, practice nurses, specialist nurses, medical students, paramedical staff, junior doctors, non-specialist doctors and all other health professionals working in both primary and secondary care.(a) Section from a cigarette smoker with normal lung function showing a nearly normal airway with small numbers of inflammatory cells. ... These cells release factors which activate fibroblasts, resulting in abnormal repair processes and bronchiolar fibrosis. ... In general, the inflammatory and structural changes in the airways increase with disease severity and persist even after smoking cessation.
|Title||:||ABC of COPD|
|Author||:||Graeme P. Currie|
|Publisher||:||John Wiley & Sons - 2010-11-04|